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Cell Observatory Journal Club

About the journal club

Interdisciplinary discussion of scientific articles helps to get a broad perspective on cell biology and microscopy techniques. Your own research can benefit greatly from this. That’s why a journal club has been set up. MSc and PhD students of all disciplines of the Faculty of Science are welcome to join. It is possible to get ECTS for participating in the journal club.

Journal club meetings 2011-2012: 21 October,  24 November, 23 December, 27 January, 23 February, 29 March, 27 April, 25 May, 22 June, 27 July

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Electron tomography reveals unbranched networks of actin filaments in lamellipodia

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Event series: 
Cell Observatory Journal Club
Chair: 
Giorgos Kosmidis
Location: 
Cell Observatory lecture room
From/To date: 
24 November 2011 - 12:00pm - 1:00pm

By Giogos Kosmidis - Cell movement is a complex phenomenon primarily driven by the actin network beneath the cell membrane.

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Systems biology

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Event series: 
Cell Observatory Journal Club
Chair: 
Bram Herpers
Location: 
Cell Observatory lecture room
From/To date: 
21 October 2011 - 12:00pm - 1:00pm

Systems Biology is a research field that combines high throughput (RNAi or chemical) screening with online-available protein network analyses to identify novel players in signaling networks. The paper that was published in Cell in April 2011 used a systems biology approach to define novel pathways and players that control antigen presentation through MHC class II. Antigen presentation is a vital part of the immune response to pathogens.

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Nucleosome organization

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Event series: 
Cell Observatory Journal Club
Chair: 
Thijn van der Heijden
Location: 
Cell Observatory lecture room
From/To date: 
23 June 2011 - 12:30pm - 2:00pm

In eukaryotic cells, DNA is compacted by the interaction of histones and DNA. A nucleosome consists of 147 base pairs of DNA wrapped around a single disc of histones. Higher order interactions between nucleosomes result in the formation of the chromosomal structure, i.e. the well known X-shaped structure.

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DNA nanostructures and devices

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Event series: 
Cell Observatory Journal Club
Chair: 
John Reif
Location: 
Cell Observatory lecture room
From/To date: 
25 May 2011 - 12:30pm - 2:00pm

Structural space of protein-protein interfaces

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Event series: 
Cell Observatory Journal Club
Chair: 
Willem-Jan Waterreus
Location: 
Cell Observatory lecture room
From/To date: 
21 April 2011 - 12:30pm - 2:00pm
  • Paper: Gao, M. and J. Skolnick "Structural space of protein-protein interfaces is degenerate, close to complete, and highly connected." Proceedings of the National Academy of Sciences 107(52):22517-22522.
  • doi: 10.1073/pnas.1012820107

High-throughput screen for tuberculosis progression

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Event series: 
Cell Observatory Journal Club
Chair: 
Wouter Veneman
Location: 
Cell Observatory lecture room
From/To date: 
24 March 2011 - 12:30pm - 2:00pm

Discovering similar regions on protein surfaces using spin-image profiles

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Event series: 
Cell Observatory Journal Club
Chair: 
Joris Slob
Location: 
Cell Observatory lecture room
From/To date: 
24 February 2011 - 12:30pm - 2:00pm

4D cryo electron microscopy: biological complexes in action

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Event series: 
Cell Observatory Journal Club
Chair: 
Marin van Heel
Location: 
Cell Observatory lecture room
From/To date: 
14 January 2011 - 12:30pm - 2:00pm